Lucille Ball Desi Arnaz Museum & Center

The Lucille Ball Desi Arnaz Museum,, formally The Lucille Ball Desi Arnaz Museum & Center for Comedy and commonly known as the Lucy Desi Museum, is a museum at 2 West 3rd Street, Jamestown, New York that is affiliated with the nearby National Comedy Center with which it shares executive director Journey Gunderson. The museum is dedicated to the lives and careers of Lucille Ball and Desi Arnaz. Jamestown was Ball's birthplace.

The museum opened in 1996 and as of 2015, drew approximately 25,000 international visitors annually. The Comedy Center followed in 2016.