Kumano Hongū Taisha is a Shinto shrine located in Tanabe, Wakayama, deep in the rugged mountains of the Kii Peninsula of Japan. It is included as part of the Kumano Sanzan in the World Heritage site "Sacred Sites and Pilgrimage Routes in the Kii Mountain Range". The main deity enshrined is Kumano Gongen. All of the ancient Kumano Kodō routes lead to the Grand Shrine.
It was originally located at present Ōyunohara, on a sandbank at the confluence of the Kumano River and Otonashi River. In 1889, it was partially destroyed in a flood and the remaining shrine buildings were relocated at its present site in 1891. Of the original five main pavilions only three were rebuilt. Four deities were moved there and the other eight are still enshrined there in two stone monuments.