West Seneca is a town in Erie County, New York, United States. The population was 44,711 at the 2010 census. West Seneca is a centrally located interior town of the county, and a suburb of Buffalo. West Seneca, Orchard Park and Hamburg form the inner "Southtowns", a cluster of middle-class suburban towns.
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Coordinates 42°50'22.5" N -78°45'14.928" E