Williamsville is a village in Erie County, New York, in the United States. The population was 5,300 at the 2010 census. The village is named after Jonas Williams, an early settler. It is part of the Buffalo–Niagara Falls Metropolitan Statistical Area.
Williamsville is located mostly within the town of Amherst, but Creek Road and Creek Heights in the south part of the village are in the town of Cheektowaga. The village is in the northeastern quadrant of Erie County.
Williamsville is also a postal ZIP code: 14221; however, that ZIP code contains large sections of the town outside the village and also includes significant commercial areas within Clarence.
Address 5773 Main St, Williamsville 14221, United States
Coordinates 42°57'50.209" N -78°44'16.113" E