Church of Santa Ana

The National Shrine of Our Lady of the Abandoned, also known as Santa Ana Church, is a Spanish colonial period Roman Catholic church located in the district of Santa Ana in Manila, Philippines. It is under the jurisdiction of the Archdiocese of Manila. The parish was established by the Franciscan missionaries in 1578 under the patronage of Saint Anne. The present stone church was constructed by Vicente Inglés from 1720 to 1725 and was dedicated to its present patron, the Our Lady of the Abandoned. The revered image of its patron was made in Valencia, Spain in 1713 and arrived in the Philippines in 1717.

The church houses two National Cultural Treasures declared by the National Museum of the Philippines: the Santa Ana Site Museum located in the convent patio and the Camarín de la Virgen. It was declared a national shrine in 2021.