La Isabela in Puerto Plata Province, Dominican Republic was the first stable Spanish settlement and town in the Americas established in December 1493. The site is 42 km west of the city of Puerto Plata, adjacent to the village of El Castillo. The area now forms a National Historic Park.
La Isabela was founded by Christopher Columbus during his second voyage, and named after Queen Isabella I of Castile. The settlement of La Navidad, established by Columbus one year earlier to the west of La Isabela in what is present day Haiti, was destroyed by the native Taíno people before he returned. La Isabela was abandoned by 1500. The only earlier European settlements in the Americas were settlements by the Vikings in Greenland and Newfoundland which dated from 500 years earlier.
Wikipedia https://en.wikipedia.org/wiki/La_Isabela
UNESCO Website http://whc.unesco.org/en/tentativelists/1706/
Address Dominican Republic
Coordinates 19°53'16.509" N -71°4'50.145" E