Istres is a commune in southern France, some 60 km northwest of Marseille. It is in the Provence-Alpes-Côte d'Azur region, in the Bouches-du-Rhône department, of which it is a subprefecture.
Wikipedia https://en.wikipedia.org/wiki/Istres
Coordinates 43°30'50.058" N 4°59'18.356" E