Winston-Salem

Winston-Salem is a city and the county seat of Forsyth County, North Carolina, United States. In 2020, the population was 249,545, making it the second-largest municipality in the Piedmont Triad region, the fifth-most populous city in North Carolina, the third-largest urban area in North Carolina, and the 90th most populous city in the United States. With a metropolitan population of 679,948 it is the fourth largest metropolitan area in North Carolina. Winston-Salem is home to the tallest office building in the region, 100 North Main Street, formerly known as the Wachovia Building and now known locally as the Wells Fargo Center.

In 2003, the Greensboro-Winston-Salem-High Point metropolitan statistical area was redefined by the OMB and separated into the two major metropolitan areas of Winston-Salem and Greensboro-High Point. The population of the Winston-Salem metropolitan area in 2020 was 679,948.