Witten Hauptbahnhof is a railway station in the town of Witten in western Germany. It is situated southwest of the town.
In 1849 the station was opened as Witten West by the Bergisch-Märkische Eisenbahn-Gesellschaft. At the end of the 19th century the whole station was reconstructed, the new station building was designed by the architect Richard Witten Sauerbruch and opened in 1901. It is now part of The Industrial Heritage Trail. In 1940 the station was renamed Witten Hauptbahnhof.